Our products & services

With both standard and highly specialised equipment at our disposal we can meet the challenges of most chemistry custom synthesis problems. A wide range of chemistry expertise within our staff also gives us direct experience across a range of synthetic areas including homogeneous catalysis, asymmetric synthesis, heterocyclic synthesis and biocatalysis.

Advance your drug discovery program with confidence. Apex Molecular provides expert medicinal chemistry services, guiding your project from initial hit identification and validation through to comprehensive lead optimization and the development of compounds with desirable drug-like characteristics. Once in the LO, we can drive the project forward through to preclinical toxicology batch and onwards to clinical nomination and GMP batch production (with our expert partner- full tech transfer provided)

Our experienced team leverages extensive knowledge to implement tailored strategies focused on enhancing potency, selectivity, and pharmacokinetic/pharmacodynamic (PK/PD) profiles. We excel in the rational design and efficient synthesis of novel chemical entities, employing state-of-the-art methodologies and a deep understanding of structure-activity relationships.

Whether you represent an emerging biotechnology firm exploring early-stage assets or a mid-sized pharmaceutical organization refining lead series, Apex Molecular offers flexible and scalable solutions to accelerate your research and development timelines. Our capabilities encompass the management of complex synthetic challenges and the strategic incorporation of specific structural features essential for your therapeutic targets. Partner with Apex Molecular to drive your discoveries towards successful clinical candidates.

Apex Molecular is a leading UK Chemistry CRO providing specialist chemistry services, including the synthesis of high potency warheads and payload compounds for use in Antibody Drug Conjugates (ADCs).

As projects progress along the development pipeline the quantities of material required for testing can change quickly. Often the initial synthesis of the target of interest was only executed on small milligrams scale and rapid scale up is required to deliver multigram quantities for further testing. Apex Molecular is well equipped and experienced in executing these rapid scale-up projects.

Every chemical synthesis has different challenges and Apex Molecular designs the bespoke project depending on the level of complexity utilising either a fee for service (FFS) or a research based full time equivalent (FTE) approach.

Through our partnership with NovaData Solutions we can provide access to and expertise in data informatics, computational chemistry and molecular modelling services for early phase drug discovery.

A selection of DNA damaging HPAPI toxins and intermediates are available to purchase directly from Apex Molecular. These compounds are synthesised in our laboratories.

A selection of linkers and intermediates are available to purchase directly from Apex Molecular. These compounds are used in predominantly in the development of ADCs and are synthesised in our laboratories.

Apex Molecular Ltd operate with a Precursor and Controlled Drugs Licence, allowing us to synthesise and store all scheduled substances for use in research projects.

Below are a list of controlled substances, metabolites and stable isotopically labelled (SIL) compounds available for purchase directly from Apex Molecular Ltd.