Case Study – Rapid Scale-Up
A virtual UK pharmaceutical company required a complex 8 step synthesis of an advanced intermediate compound under a tight timeline.The project required rapid scale up as previously the compound had only been synthesised in low gram quantities and 50 g of material was required.
The project was initiated on 200g scale (20L reactor) and a number of parameters were optimised ahead of manufacture, including improved reaction conditions for the final step that increased the product recovery and purity. Overall the project delivered 60 g of product in 6 weeks.
Read More